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Category Archives: Ischemia-Reperfusion Injury
Liquid Assisted Pulmonary Cooling in Cardiopulmonary Cerebral Resuscitation – Part 1
Table of Contents Introduction………………………………………………………………………………………………………. 6 Table of Abbreviations, Symbols and Acronyms………………………………………….. 9 Section I: Introducing Liquid Assisted Pulmonary Cooling………………………… 14 Liquid Assisted Pulmonary Cooling in Cardiopulmonary Cerebral Resuscitation, Introduction ………………………………………………………………………………………………………………….. 15 Hypothermia as an Active Therapeutic Agent ………………………………………………………………………………………………………………….. 17 The … Continue reading
Induction of Hypothermia in the Cryonics Patient: Theory and Technique, Part 2
By Mike Darwin External Cooling Using the Portable Ice Bath (PIB) The first generation PIBs consisted of a waterproof vinyl tank which snapped to a rigid frame of 1-1/4″ OD PVC plastic pipe. The PIB could be partially broken down … Continue reading
Induction of Hypothermia in the Cryonics Patient: Theory and Technique, Part 1
By Mike Darwin Understanding Hypothermia The Q10 Rule and Protective Hypothermia Hypothermia is widely understood to protect against ischemia by virtue of its ability to slow metabolic rate. In man, each 10oC decrement of temperature reduction (below 37oC) results in … Continue reading
A Visit to Alcor
“Are you interested in the whole body or the neuro? And would you like fries and a Coke with that?” By Mike Darwin Introduction A short while ago, I hosted 3 visitors from the Russian cryonics organization KrioRus. During … Continue reading
You be the Judge: Understanding and Evaluating the Quality of Human Cryopreservations from Cryonics Organization Literature and Case Report Data, Part 2
By Mike Darwin Defining the Cryonics Organization When cryonics began in the 1960s, the mission of the 4 cryonics societies[1] that more or less simultaneously came into existence at that time was fairly homogenous: 1) Make cryopreservation available to their … Continue reading
You be the Judge: Understanding and Evaluating the Quality of Human Cryopreservations from Cryonics Organization Literature and Case Report Data, Part 1
By Mike Darwin Introduction A short while ago, these remarks were posted in the comments section of Chronosphere: “I’ve often heard it said that case reports have been very inconsistent. I’ve read a haphazard sampling of Alcor case reports. They … Continue reading
I Know this is Going to be Shocking: A Review of Wearable Continuous Monitoring Systems to Detect and Treat Sudden Cardiac Arrest in Cryonicists
By Mike Darwin The problem of a cryonicist experiencing sudden cardiac arrest (SCA) unattended is hardly theoretical. This has occurred a number of times already, with some patients going upwards of a week before being discovered. Because SCA is only … Continue reading
Last Aid as First Aid for Cryonicists, Part 5
Unarguably one of the simplest, and also the most powerful and effective cryonics first aid measures, is to cool the patient. At first glance, this would seem to require little in the way of preparation. After all, how hard is it to get ice and put it on the patient? The answer depends on the answers to two other questions: “How quickly do you want it done” and “where do you live?” Continue reading
Last Aid as First Aid for Cryonicists, Part 4
In situations where irreversibility has been established by a properly executed medical directive not to pursue cardiopulmonary resuscitation (CPR) or defibrillation (especially in cases where the patient is of advanced age, in poor health, or is terminally), it still necessary to objectively determine and document cardiopulmonary arrest. Continue reading
Last Aid as First Aid for Cryonicists, Part 3
By Mike Darwin Sudden Death and Unexpected Death: Is there a Difference and Does it Matter? Most cryonicists understand what sudden death is: it is cardiac arrest due to sudden cardiac arrest (SCA), rapidly fatal stroke, accident, homicide, and yes, even … Continue reading